Dr.Reju-All Advanced PDRN Rejuvenating Mask is a face-and-neck sheet-mask set with 1,200 ppm PDRN positioning. The current official U.S. brand page now provides the full INCI list and 15–20 minute directions, so the product can be evaluated more precisely than an older retailer summary allowed.
Quick answer
The official Dr.Reju-All U.S. page lists a face sheet plus neck strip, 15–20 minute wear time, and a fragrance-free formula containing water, glycerin, butylene glycol, niacinamide, sodium hyaluronate, hydrolyzed collagen, copper tripeptide-1, panthenol, allantoin, adenosine, sodium DNA, trehalose, betaine, and supporting ingredients. The brand markets the mask around 1,200 ppm PDRN. That number is a label fact. It does not by itself prove regeneration, wrinkle correction, or clinical equivalence to injectable or medical PDRN.
Pack facts and what one use includes
The ProtoClinical SKU is Dr.Reju-All Advanced PDRN Rejuvenating Mask 36 ml × 6ea. The current Shopify catalog confirms one box with six uses. The brand directions describe each use as a face mask plus a neck strip.
| Pack fact | What it means |
|---|---|
| 36 ml × 6ea | Six single-use mask packets in the ProtoClinical SKU. |
| Face sheet + neck strip | One session covers both areas with separate pieces. |
| 15–20 minutes | Current official U.S. brand wear time. Longer is not automatically better. |
| 1,200 ppm PDRN positioning | A disclosed concentration statement, but not a clinical-outcome guarantee. |
How to use the mask
- Cleanse and tone if toner is part of your routine.
- Open the packet and unfold the mask using the backing sheet.
- Align the face sheet with the eyes and mouth, then place the neck strip below the chin.
- Leave on for 15–20 minutes.
- Remove and gently pat remaining serum into the skin.
The official page also suggests using leftover serum on the neck, hands, or décolletage. For hygiene, the single-use sheet itself should not be reused. If skin becomes significantly uncomfortable, remove it rather than extending the session.
What the current INCI list tells us
The official U.S. formula begins with water, glycerin, butylene glycol, niacinamide, 1,2-hexanediol, sodium hyaluronate, hydrolyzed collagen, copper tripeptide-1, panthenol, allantoin, adenosine, sodium DNA, trehalose, and betaine, followed by texture and preservation support ingredients. This is a multi-ingredient hydrating sheet-mask formula, not “PDRN alone.”
That distinction matters when discussing results. Glycerin, sodium hyaluronate, trehalose, and betaine can contribute to a hydration-focused formula. Panthenol and allantoin are commonly used for comfort. Niacinamide and adenosine have their own cosmetic evidence bases. If a finished mask makes skin look temporarily smoother or more dewy, the effect cannot be assigned to sodium DNA alone without product-specific testing designed to isolate that factor.
What “PDRN” can and cannot mean here
The official INCI list names Sodium DNA, while the product marketing uses PDRN terminology. Cosmetic ingredient naming, source disclosure, molecular distribution, and medical PDRN terminology are not automatically the same thing. The current official product page says salmon-derived DNA in its FAQ, but that brand statement still does not establish molecular equivalence to every PDRN material used in medical literature.
Do not borrow results from injected PDRN, wound-care products, or unrelated serum studies and apply them to this sheet mask. The correct evidence lane is the exact mask, under the exact conditions in which it was tested.
Where it belongs in a routine
This is an optional hydration-focused treatment step, not a replacement for cleanser, moisturizer, or sunscreen. It fits most naturally after cleansing and before moisturizer in an evening routine. If you use it in the day, sunscreen remains the final skincare step on exposed face and neck.
A first trial is easier to interpret when you do not combine it with a new exfoliating acid, retinoid, peel, or other unfamiliar active on the same night. The mask is already a prolonged-contact format. A simple routine gives you a clearer read on comfort.
Value per use
ProtoClinical's live Shopify price was US$33.75 on September 15, 2026 for the six-pack, which equals approximately US$5.63 per face-and-neck session. Price can change, so the durable comparison method is current box price ÷ 6. Use the live PDP for the current number before buying.
That per-use value should be compared with other single-use masks, not with the price per milliliter of a serum bottle. A mask includes the sheet format, one-time packaging, and a fixed session. It is a different purchase model from a daily serum or cream.
Who may prefer this mask
It may suit someone who wants a fragrance-free, face-and-neck sheet-mask ritual and values a hydrating multi-ingredient formula. It may be less attractive if you dislike single-use formats, want a daily product at a lower cost per application, or need stronger finished-product evidence for anti-aging claims before spending.
The brand recommends two to three uses per week, but that is manufacturer guidance rather than a medical requirement. Frequency should still fit budget, comfort, and the rest of the routine.
Why the finished formula matters more than the hero ingredient
The mask combines several humectants and skin-conditioning ingredients in one prolonged-contact format. That creates a different exposure from applying a few drops of a serum. The sheet also changes evaporation and keeps the liquid against the surface for 15–20 minutes. As a result, a temporary hydrated or plumper-looking finish can come from the whole system: water, humectants, sheet occlusion, film-formers, and the way light reflects from moisturized skin.
This is why a before-and-after mirror check immediately after removal is weak evidence for a PDRN-specific claim. If you want to judge whether the product is worth repeating, look at comfort after the serum has settled, whether moisturizer layers well afterward, and whether you value the face-and-neck format enough to use the remaining packets.
Label literacy: Sodium DNA, PDRN, and source
The official INCI uses Sodium DNA, which is the standardized ingredient name visible to the consumer. The product marketing uses PDRN and the FAQ says salmon-derived DNA. Those statements can coexist, but they answer different questions: INCI tells you how the ingredient is declared on the cosmetic label; the brand's PDRN wording describes the commercial ingredient story; source disclosure adds another layer.
None of those alone provides molecular-weight distribution, fragment-length distribution, purity specification, manufacturing process, or equivalence to a material used in a medical publication. If a comparison claims that one PDRN mask is “stronger” solely because its ppm is higher, it is ignoring most of the variables that would be needed for a scientifically meaningful comparison.
Tolerance and when not to use it
The brand describes the formula as suitable for sensitive skin, but no cosmetic can be guaranteed reaction-free for every person. Use it on intact skin. If the face or neck is already burning, peeling, swollen, or reacting to another product, postponing the mask gives you a clearer baseline. Remove the sheet if discomfort becomes significant rather than waiting out the full time.
Persistent rash, hives, swelling, eye-area involvement, or significant burning are not routine “purging” signals from a hydrating sheet mask. Stop use and seek appropriate medical advice when symptoms are important or do not settle.
FAQ
How long should the Dr.Reju-All PDRN mask stay on?
The current official U.S. direction is 15–20 minutes.
Is the formula fragrance-free?
The current official U.S. page states that it is fragrance-free, and the published INCI list does not list parfum/fragrance.
Does 1,200 ppm prove that it works better than a lower-ppm PDRN product?
No. Concentration is only one variable. Material identity, source, molecular distribution, vehicle, application, and finished-product evidence also matter.
Can the mask replace moisturizer?
It can add a temporary hydrating step, but use moisturizer afterward if your skin still needs it.
Sources and verification notes
- Dr.Reju-All Official U.S. Store: Advanced PDRN Rejuvenating Mask. Used for current directions, INCI list, fragrance-free statement, and 1,200 ppm positioning.
- Connected ProtoClinical Shopify product record for the exact 36 ml × 6ea SKU, checked September 15, 2026.
Verification date: September 15, 2026. Brand claims are identified as brand claims; this guide does not equate cosmetic Sodium DNA/PDRN wording with medical or injectable PDRN evidence.
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