ProtoClinical k-beauty IOPE RETINOL RETI-JECTION SERUM 30ml in deep blue serum packaging with a white top on a light background
ProtoClinical k-beauty IOPE RETINOL RETI-JECTION SERUM 30ml in deep blue serum packaging with a white top on a light background
ProtoClinical k-beauty IOPE RETINOL RETI-JECTION SERUM 30ml in dark serum packaging with a pale blue top on a light background
IOPE

IOPE RETINOL RETI-JECTION SERUM 30ml

$55.20
Supports visible firmness and a lifted, contoured appearance Restores skin's natural bounce and elasticity Softens the look of fine lines with consistent use Restores healthy radiance and a lit-from-within glow
This innovative serum delivers retinol deep into the skin using 3 million precision-engineered spicules, maximizing ingredient penetration for fast, visible results. Powered by 2% Retinol RX™, it significantly boosts elasticity, reduces wrinkles, and refines pores—delivering up to +49% firmness, –83% wrinkles and +88% radiance in human trials. The...
For all skin types dealing with sensitivity and redness: IOPE's serum with Retinol works from within to deliver supports visible firmness and a lifted, contoured appearance, not just temporary comfort.
100% authentic

Sourced direct · batch code

30-day returns

Unopened, no quibble

Korean Beauty Formulation Suitable for Daily Use
Retinol/Vitamin A Hyaluronic Acid Spicules
IOPE RETINOL RETI-JECTION SERUM 30ml
IOPE RETINOL RETI-JECTION SERUM 30ml Default Title
$55.20
Clinically proven actives Dermatologist tested 100% authentic Korean Cruelty-free
What's inside ·

Retinol/Vitamin A, the repair molecule

Retinol converts to retinoic acid inside the skin, where it binds to nuclear receptors that regulate gene expression for cell turnover and collagen production. In IOPE RETINOL RETI's serum, Retinol targets sensitivity and redness, delivering supports visible firmness and a lifted, contoured appearance with consistent use.
Retinol 2%
accelerates cell turnover and stimulates collagen synthesis for smoother, firmer skin
The texture

Lightweight, absorbing serum

This innovative serum delivers retinol deep into the skin using 3 million precision-engineered spicules, maximizing ingredient penetration for fast, visible results. Powered by 2% Retinol RX™, it significantly boosts elasticity, reduces wrinkles, and refines pores—delivering up to +49% firmness, –83% wrinkles and +88% radiance in human trials. The advanced spicule delivery system penetrates 46% deeper and faster than conventional formulations, offering potent care with minimal irritation. A breakthrough in high-performance skincare that combines clinical-grade efficacy with gentle, targeted action.

Oily Skin Dry Skin Pores Blackheads Brightening Radiance Wrinkles Fine Lines Loss of Firmness Elasticity Redness Irritation
Hover the swatch — it ripples like water

How to use

1

Step 1: After cleansing and toning, press 2 to 3 drops onto fingertips.

2

Step 2: Gently pat and press across forehead, cheeks, nose, and chin.

3

Step 3: Allow 30 seconds for full absorption before the next step.

4

Step 4: Follow with moisturizer. Use sunscreen in the morning.

Full transparency

Ingredients

Retinol accelerates cell turnover and stimulates collagen synthesis for smoother, firmer skin. This focused formula puts all its power behind one proven active for maximum impact.

Retinol converts to retinoic acid inside the skin, where it binds to nuclear receptors that regulate gene expression for cell turnover and collagen production. Unlike prescription retinoids that work immediately (and irritate), retinol converts gradually, offering a sustained effect with less downtime. The compounding effect means texture, fine lines, and tone all improve progressively over 8 to 12 weeks.

The detail

Specs & details

FormatLightweight serum
SizeDefault Title
Skin typesAll Skin Types
Country of originSouth Korea
Pairs beautifully with

Complete the routine

Build your routine Tick products to add them with this one
$55.20
Before you add to cart

Questions & answers

After cleansing and toning, before moisturizer. Serums deliver actives most effectively on freshly prepped skin.
Yes. Apply from thinnest to thickest consistency and allow each layer to absorb before the next.
Most users notice initial improvement within 2 to 4 weeks. For full benefits like supports visible firmness and a lifted, contoured appearance, allow 6 to 8 weeks of consistent use.
Your skin begins adjusting. You may notice improved hydration and comfort before more visible changes like texture refinement become apparent.
Yes, this formula is developed to be compatible with all skin types dealing with sensitivity and redness. If you have very reactive skin, patch test on the inner arm before full application.
The formula is designed to be well-tolerated. For pregnancy-specific concerns, consult your healthcare provider. For sensitive skin, patch test before full application.
Retinol accelerates cell turnover and stimulates collagen synthesis for smoother, firmer skin. Consistent daily use is key to seeing the full benefits.
Check the INCI list for the most accurate information on fragrance components. The formula is developed for minimal irritation potential.
Store in a cool, dry place away from direct sunlight. Use within 12 months of opening for optimal freshness and efficacy.
Serums have a higher concentration of targeted actives than essences and a lighter consistency than most ampoules. They deliver the most potent treatment in your routine.
You may also like

More clinical glow

IOPE
About the brand

OriginSeoul, KR
Shop all →