ProtoClinical k-beauty IOPE Stem III Signature Set single front-facing beige skincare set box centered on a white background
ProtoClinical k-beauty IOPE Stem III Signature Set front-facing beige packaging on a white background
ProtoClinical k-beauty IOPE Stem III Signature Set single beige skincare set box centered on a soft neutral background
IOPE

IOPE Stem III Signature Set

$55.35
Visibly brightens skin tone and fades uneven patches Provides intensive moisture that sinks in without heaviness Plumps fine lines from below for a filled-in, youthful look Calms irritation and reactive redness on contact Targets visible signs of aging for a more youthful appearance
THE ULTIMATE ANTI-AGING SOLUTION: IOPE's STEM III-the three key ingredients(Allantoin(moisturization), Spiraeoside(Revitalization), Peptides(Plumping))-strengthens the weakened skin's moisture barrier and recharges tired aged skin. PATENTED ALLANTO-COMPLEX FORMULA FOR VISIBLE IMPROVEMENT: This cutting-edge ingredient formulation shows improvement in five indicators-The look of skin texture, radiance, moisture level, transparency and amount of...
For all skin types dealing with fine lines and wrinkles: IOPE's ampoule with Peptides works from within to deliver visibly brightens skin tone and fades uneven patches, not just temporary comfort.
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Korean Beauty Formulation Concentrated Formula
Hyaluronic Acid Peptides Panthenol Pearl Allantoin Oat Amino Acids Sage
IOPE Stem III Signature Set
IOPE Stem III Signature Set Default Title
$55.35
Clinically proven actives Dermatologist tested 100% authentic Korean Cruelty-free
What's inside ·

Hyaluronic Acid, the repair molecule

Peptides are short chains of amino acids that act as chemical messengers inside the skin. When applied topically, they mimic the signals that trigger collagen synthesis, essentially nudging the skin into repair mode. In this ampoule, Peptides targets fine lines and wrinkles, delivering visibly brightens skin tone and fades uneven patches with consistent use.
Peptides
signal the skin to produce more collagen through its own natural repair pathways
Allantoin
neutralizes irritation signals while promoting gentle cell regeneration
Panthenol (Vitamin B5)
penetrates deep to hydrate from within and repair compromised barrier tissue
The texture

Lightweight, concentrated gel

  • THE ULTIMATE ANTI-AGING SOLUTION: IOPE's STEM III-the three key ingredients(Allantoin(moisturization), Spiraeoside(Revitalization), Peptides(Plumping))-strengthens the weakened skin's moisture barrier and recharges tired aged skin.
  • PATENTED ALLANTO-COMPLEX FORMULA FOR VISIBLE IMPROVEMENT: This cutting-edge ingredient formulation shows improvement in five indicators-The look of skin texture, radiance, moisture level, transparency and amount of dead skin cells.
  • DEEP MOISTURIZING WITH HYALURONIC AND AMINO ACIDS: The combination of these two penetrates deep to restore moisture and nourish the skin. Gel type toner is non-greasy, gets absorbed quickly and is ideal for daily AM/PM skin care routine.
  • SKIN BRIGHTENING EFFECT: Panthenol and beta-glucan in the facial moisturizer and toner set help to soothe dry, sun-damaged skin and reduce redness or inflammation. Regular usage will promote a pearlescent glow. usage will promote a pearlescent glow.
  • IOPE STEM III Softener 80ml
  • IOPE STEM III Ampoule 30ml
  • IOPE STEM III Emulsion 80ml
Oily Skin Dry Skin Combination Skin Sensitive Reactive Mature Aging Dull Pigmented Men's Skin Oil Control Shine Brightening Radiance Loss of Firmness Elasticity Barrier Repair Protection Redness Irritation Roughness Texture
Hover the swatch — it ripples like water

How to use

1

Step 1: After cleansing and toning, press 2 to 3 drops onto fingertips.

2

Step 2: Gently pat and press across forehead, cheeks, nose, and chin.

3

Step 3: Allow 30 seconds for full absorption before the next step.

4

Step 4: Follow with moisturizer. Use sunscreen in the morning.

Full transparency

Ingredients

Peptides signal the skin to produce more collagen through its own natural repair pathways, Allantoin neutralizes irritation signals while promoting gentle cell regeneration, and Panthenol (Vitamin B5) completes the formula as a penetrates deep to hydrate from within and repair compromised barrier tissue.

Peptides are short chains of amino acids that act as chemical messengers inside the skin. When applied topically, they mimic the signals that trigger collagen synthesis, essentially nudging the skin into repair mode. Unlike retinol, which forces cellular turnover (and can irritate), peptides work through the skin's own natural pathways, making them particularly effective for daily use without downtime or sensitivity.

The detail

Specs & details

FormatConcentrated ampoule
SizeDefault Title
Skin typesAll Skin Types
Country of originSouth Korea
Pairs beautifully with

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$55.35
Before you add to cart

Questions & answers

After cleansing and toning, before moisturizer. Ampoules deliver concentrated actives most effectively on freshly prepped skin.
Yes, ampoules are concentrated enough to serve as your primary active step. Follow with moisturizer to seal in benefits.
Most users notice initial improvement within 2 to 4 weeks. For full benefits like visibly brightens skin tone and fades uneven patches, allow 6 to 8 weeks of consistent use.
Your skin begins adjusting. You may notice improved hydration and comfort before more visible changes like texture refinement become apparent.
Yes, this formula is developed to be compatible with all skin types dealing with fine lines and wrinkles. If you have very reactive skin, patch test on the inner arm before full application.
The formula is designed to be well-tolerated. For pregnancy-specific concerns, consult your healthcare provider. For sensitive skin, patch test before full application.
Peptides signal the skin to produce more collagen through its own natural repair pathways. Consistent daily use is key to seeing the full benefits.
Check the INCI list for the most accurate information on fragrance components. The formula is developed for minimal irritation potential.
Store in a cool, dry place away from direct sunlight. Use within 12 months of opening for optimal freshness and efficacy.
Ampoules typically have a higher concentration of actives than serums. They are designed as intensive treatment boosters, often used during periods when skin needs extra support.
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About the brand

OriginSeoul, KR
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