MEDICUBE: Centellascar Ointment (15g)

Centella Asiatica calms inflammation and accelerates barrier recovery through its four key compounds. This focused formula puts all its power behind one proven active for maximum impact.

The management of localized cutaneous injuries and scar tissue requires the precision delivery of triterpenoids.
The Centella Scar Ointment utilize a high concentration of Centella Asiatica Titrated Extract (CATE), which includes madecassoside, asiaticoside, and asiatic acid in a standardized ratio.
Mechanistically, these bioactive molecules stimulate the synthesis of type I collagen and fibronectin, which are the fundamental structural components of the extracellular matrix during the tissue remodeling phase.
By activating the SMAD signaling pathway within the fibroblasts, the ointment accelerates the closure of micro-wounds and improves the mechanical strength of the newly formed tissue.
This process is essential for preventing the formation of hypertrophic scars and post-inflammatory erythema.
Furthermore, the ointment provides a robust anti-inflammatory action by inhibiting the production of pro-inflammatory cytokines such as IL-1β and TNF-α.
This reduction in the inflammatory cascade is critical for calming localized redness and preventing the oxidative stress that leads to cell death in compromised areas.
The occlusive nature of the ointment base creates a secondary skin barrier, significantly reducing transepidermal water loss (TEWL) and maintaining the hydration levels necessary for enzymatic repair processes.
Clinical evidence supports the use of Centella titrated extracts for the treatment of surgical scars, minor burns, and persistent irritation.
By providing a stable, protective environment and a high-purity biological stimulus, the formulation ensures that the skin returns to its natural state of homeostasis as quickly as possible.
This scientific approach to scar management ensures that the skin remains resilient and aesthetically uniform.
The formula is hypoallergenic and safe for use on sensitive or post-procedure skin where the barrier has been temporarily disrupted, fulfilling the requirements for professional-level clinical care.