ProtoClinical k-beauty MEDICUBE: Deep Vita A Retinol Serum (30ml) single upright beige serum bottle on a muted taupe background
ProtoClinical k-beauty MEDICUBE: Deep Vita A Retinol Serum (30ml) single upright beige serum bottle on a muted taupe background
ProtoClinical k-beauty MEDICUBE: Deep Vita A Retinol Serum (30ml) single upright beige serum bottle with a dark cap on a pale cream background
ProtoClinical k-beauty MEDICUBE: Deep Vita A Retinol Serum (30ml) single upright beige serum bottle with a dark cap on a muted sage gray background
ProtoClinical k-beauty MEDICUBE: Deep Vita A Retinol Serum (30ml) single upright beige serum bottle with a dark cap on a white background with pink and green accents
ProtoClinical k-beauty MEDICUBE: Deep Vita A Retinol Serum (30ml) single upright beige serum bottle with a dark cap on a pale pink background with gray-green accents
medicube

MEDICUBE: Deep Vita A Retinol Serum (30ml)

$33.35
Visibly brightens skin tone and fades uneven patches Targets visible signs of aging for a more youthful appearance Fades the look of dark spots and post-inflammatory marks
7-LAYER RETINOL REGENERATIVE SYSTEMThis powerful anti-aging serum utilizes seven distinct layers of retinol to maximize delivery and minimize irritation. It targets deep wrinkles and uneven texture by accelerating cellular turnover.LUMINOUS REPAIREnriched with Niacinamide and Squalane, it brightens dark spots and repairs damaged barrier lipids. The formula provides a...
For all skin types dealing with sensitivity and redness: medicube's serum with Niacinamide works from within to deliver visibly brightens skin tone and fades uneven patches, not just temporary comfort.
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Korean Beauty Formulation Suitable for Daily Use
Retinol/Vitamin A Niacinamide Hyaluronic Acid Collagen Panthenol Squalane
MEDICUBE: Deep Vita A Retinol Serum (30ml)
MEDICUBE: Deep Vita A Retinol Serum (30ml) Default Title
$33.35
Clinically proven actives Dermatologist tested 100% authentic Korean Cruelty-free
What's inside ·

Retinol/Vitamin A, the repair molecule

Niacinamide works at the junction between melanocytes and keratinocytes, intercepting melanin transfer before pigment reaches the visible surface. It simultaneously boosts ceramide synthesis to strengthen the lipid barrier, which is why consistent use addresses both discoloration and dehydration. In this serum, Niacinamide targets sensitivity and redness, delivering visibly brightens skin tone and fades uneven patches with consistent use.
Niacinamide
intercepts melanin transfer to fade spots and refine pore texture from within
Retinol
accelerates cell turnover and stimulates collagen synthesis for smoother, firmer skin
Squalane
mimics the skin's own oils for lightweight, non-clogging hydration
The texture

Lightweight, absorbing serum

7-LAYER RETINOL REGENERATIVE SYSTEM

This powerful anti-aging serum utilizes seven distinct layers of retinol to maximize delivery and minimize irritation. It targets deep wrinkles and uneven texture by accelerating cellular turnover.

LUMINOUS REPAIR

Enriched with Niacinamide and Squalane, it brightens dark spots and repairs damaged barrier lipids. The formula provides a controlled release of Vitamin A for consistent, long-term skin health.

Combination Skin Mature Aging Dull Pigmented Acne Breakouts Hyperpigmentation Dark Spots Brightening Radiance
Hover the swatch — it ripples like water

How to use

1

How to use:

2

• Step 1: Apply a pea-sized amount to clean, dry skin (PM only).

3

• Step 2: Use every other night initially to build tolerance.

4

• Step 3: Gently massage until fully absorbed.

5

• Step 4: Always follow with a ceramide-rich moisturizer and SPF the next morning.

Full transparency

Ingredients

Niacinamide intercepts melanin transfer to fade spots and refine pore texture from within, Retinol accelerates cell turnover and stimulates collagen synthesis for smoother, and Squalane completes the formula as a mimics the skin's own oils for lightweight.

Retinoids are recognized as the gold standard in clinical anti-aging due to their unique ability to interact with nuclear receptors in skin cells.
The Deep Vita A Retinol Serum utilizes a 7-layer delivery system to ensure that Vitamin A reaches the target layers of the epidermis without causing the erythema and flaking associated with traditional formulas.
Mechanistically, retinol is converted by the skin into retinoic acid, which then binds to Retinoic Acid Receptors (RAR) and Retinoid X Receptors (RXR).
This binding triggers the transcription of genes responsible for cellular proliferation and the synthesis of the extracellular matrix.
Specifically, it upregulates the production of type I and type III collagen while inhibiting the enzymes that break down elastin.
This results in a visible thickening of the dermal layer and a reduction in the appearance of fine lines and deep wrinkles.
To complement this regenerative action, the formula incorporates Niacinamide and Squalane.
Niacinamide functions by blocking the transfer of melanosomes, which helps to fade the dark spots that often accompany aging.
Squalane, a skin-identical lipid, provides an immediate emollient effect, replenishing the barrier and preventing the transepidermal water loss that can lead to irritation during the retinization period.
Panthenol and Collagen provide additional hydration and soothing support, ensuring that the skin remains resilient and healthy throughout the treatment cycle.
Clinical observation confirms that this multi-layered approach results in a significant improvement in skin texture, pore visibility, and overall luminosity.
By facilitating a controlled and steady cellular turnover, the serum reveals a smoother, more youthful complexion while supporting the skin's natural repair mechanisms through evidence-based molecular science.
This protocol ensures high-performance results with professional-level safety standards.

The detail

Specs & details

FormatLightweight serum
SizeDefault Title
Skin typesAll Skin Types
Country of originSouth Korea
Pairs beautifully with

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$33.35
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Questions & answers

After cleansing and toning, before moisturizer. Serums deliver actives most effectively on freshly prepped skin.
Yes. Apply from thinnest to thickest consistency and allow each layer to absorb before the next.
Most users notice initial improvement within 2 to 4 weeks. For full benefits like visibly brightens skin tone and fades uneven patches, allow 6 to 8 weeks of consistent use.
Your skin begins adjusting. You may notice improved hydration and comfort before more visible changes like texture refinement become apparent.
Yes, this formula is developed to be compatible with all skin types dealing with sensitivity and redness. If you have very reactive skin, patch test on the inner arm before full application.
The formula is designed to be well-tolerated. For pregnancy-specific concerns, consult your healthcare provider. For sensitive skin, patch test before full application.
Niacinamide intercepts melanin transfer to fade spots and refine pore texture from within. Consistent daily use is key to seeing the full benefits.
Check the INCI list for the most accurate information on fragrance components. The formula is developed for minimal irritation potential.
Store in a cool, dry place away from direct sunlight. Use within 12 months of opening for optimal freshness and efficacy.
Serums have a higher concentration of targeted actives than essences and a lighter consistency than most ampoules. They deliver the most potent treatment in your routine.
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About the brand

OriginSeoul, KR
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