ProtoClinical k-beauty MEDICUBE: PDRN Lip Sleeping Mask (10ml) shown as a close-up pink jar with a glossy translucent lid and pink-and-clear cream swirls above on a white background
ProtoClinical k-beauty MEDICUBE: PDRN Lip Sleeping Mask (10ml) shown as a close-up pink jar with a glossy translucent lid and pink-and-clear cream swirls above on a white background
ProtoClinical k-beauty MEDICUBE: PDRN Lip Sleeping Mask (10ml) close-up pink jar with a glossy translucent lid and pink cream swirls on a white background
ProtoClinical k-beauty MEDICUBE: PDRN Pink Collagen Gel Toner Pad / (70pads) (120ml) single rosy pink container centered in a vertical layout on a pale aqua and white background
ProtoClinical k-beauty MEDICUBE: PDRN Lip Sleeping Mask (10ml) single pink jar centered in a vertical layout on a pale aqua and white background
ProtoClinical k-beauty MEDICUBE: PDRN Lip Sleeping Mask (10ml) single pink jar centered in a vertical layout on a pale aqua and white background
medicube

MEDICUBE: PDRN Lip Sleeping Mask (10ml)

$12.28
Delivers deep, lasting hydration that keeps skin plump throughout the day Provides intensive moisture that sinks in without heaviness Restores healthy radiance and a lit-from-within glow
REGENERATIVE LABIAL VOLUME CAREThis lip sleeping mask combines Salmon PDRN and Collagen to restore the delicate labial barrier. It provides an intensive moisture boost and enhances natural radiance.STRUCTURAL HYDRATIONSpecifically designed for dry lips, it replenishes essential proteins to improve fullness. It ensures long-lasting comfort throughout the nocturnal repair...
When your skin needs a reset: Collagen in medicube's concentrated treatment that delivers delivers deep, lasting hydration that keeps skin plump throughout the day in minutes.
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Korean Beauty Formulation Intensive Treatment
Collagen PDRN
MEDICUBE: PDRN Lip Sleeping Mask (10ml)
MEDICUBE: PDRN Lip Sleeping Mask (10ml) Default Title
$12.28
Clinically proven actives Dermatologist tested 100% authentic Korean Cruelty-free
What's inside ·

Collagen, the repair molecule

Topical collagen molecules are too large to penetrate deep into the dermis, but they serve a critical role on the surface: forming a moisture-retaining film that mimics the skin's natural collagen matrix. In this mask, Collagen targets uneven texture, delivering delivers deep, lasting hydration that keeps skin plump throughout the day with consistent use.
Collagen
replenishes surface-level structural support for bounce and plumpness
PDRN
stimulates cellular repair at the DNA level for tissue regeneration and firming
The texture

Intensive, soothing

REGENERATIVE LABIAL VOLUME CARE

This lip sleeping mask combines Salmon PDRN and Collagen to restore the delicate labial barrier. It provides an intensive moisture boost and enhances natural radiance.

STRUCTURAL HYDRATION

Specifically designed for dry lips, it replenishes essential proteins to improve fullness. It ensures long-lasting comfort throughout the nocturnal repair phase.

All Skin Types Brightening Radiance
Hover the swatch — it ripples like water

How to use

1

How to use:

2

• Step 1: Apply a generous layer to the lips before sleep.

3

• Step 2: Massage gently to facilitate PDRN absorption.

4

• Step 3: Leave on overnight for structural repair.

5

• Step 4: Use during the day for continuous hydration if needed.

Full transparency

Ingredients

Collagen replenishes surface-level structural support for bounce and plumpness, while PDRN stimulates cellular repair at the DNA level for tissue regeneration and firming, creating a formula that addresses multiple needs at once.

The lips are uniquely vulnerable to environmental dehydration due to the absence of sebaceous glands and the thinness of the stratum corneum.
The PDRN Lip Sleeping Mask addresses these physiological challenges through the delivery of Salmon PDRN (Polydeoxyribonucleotide) and hydrolyzed collagen.
PDRN functions as a cell-signaling molecule that binds to adenosine receptors, stimulating the synthesis of the extracellular matrix within the labial tissue.
This biological action is essential for increasing lip fullness and smoothing the fine vertical lines associated with chronological aging.
Mechanistically, the collagen fragments provide a hygroscopic reservoir on the surface, drawing moisture into the deeper layers and creating a protective film that prevents transepidermal water loss (TEWL).
This film is reinforced with a blend of skin-identical lipids that integrate into the barrier, ensuring long-lasting suppleness.
Clinical observation confirms that the consistent use of this nucleotide-rich formula improves the skin's micro-relief and enhances the natural luminosity of the lips.
By maintaining a state of hyper-hydration for eight hours during the sleep cycle, the mask facilitates the repair of micro-fissures and reduces the sensitivity caused by external stressors.
The result is a measurable increase in lip volume and a significant improvement in texture and hydration.
This scientific approach to labial care moves beyond simple emollients to provide a regenerative stimulus that recalibrates the tissue’s health and resilience, fulfilling the requirements for professional-grade lip maintenance in a clinical skincare regimen.
The formula is designed to integrate seamlessly into the lips' delicate architecture, providing a smooth and candy-like glow that reflects the underlying health of the restored tissue.

The detail

Specs & details

FormatTreatment mask
SizeDefault Title
Skin typesAll Skin Types
Country of originSouth Korea
Pairs beautifully with

Complete the routine

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$12.28
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Questions & answers

2 to 3 times per week for maintenance. Daily use is fine during periods of extra skin stress.
No. Pat the remaining essence into your skin for maximum benefit.
Most users notice initial improvement within 2 to 4 weeks. For full benefits like delivers deep, lasting hydration that keeps skin plump throughout the day, allow 6 to 8 weeks of consistent use.
Your skin begins adjusting. You may notice improved hydration and comfort before more visible changes like texture refinement become apparent.
Yes, this formula is developed to be compatible with all skin types dealing with uneven texture. If you have very reactive skin, patch test on the inner arm before full application.
Start with once a week and monitor your skin's response. The concentrated formula may be intense for very reactive skin.
Collagen replenishes surface-level structural support for bounce and plumpness. Consistent daily use is key to seeing the full benefits.
Check the INCI list for the most accurate information on fragrance components. The formula is developed for minimal irritation potential.
Store in a cool, dry place away from direct sunlight. Use within 12 months of opening for optimal freshness and efficacy.
The extended contact time (15 to 20 minutes) allows a much higher concentration of actives to penetrate compared to a rinse-off or leave-on product.
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About the brand

OriginSeoul, KR
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